THE POLYMER SOCIETY OF KOREA

연구논문 초록집

초록 검색

세션명 콜로이드 및 분자조립 부문위원회 (I)
발표장 제3회장
논문코드 1L3-7
발표일 2021-10-21
발표시간 16:50-17:15
논문제목 Generation of ion-selective artificial membranes
발표자 오승수
발표자 소속 포항공과대학교(POSTECH)
저자 유혜빈, 오승수
소속 포항공과대학교(POSTECH)
논문초록 Cell membranes are selectively permeable to ions, which is essential for cellular survival. The control of ion permeability is delicately regulated by ion channels, wherein ion-binding motifs are located in a row, providing a continuous pathway for ions to selectively pass through the cell membranes. Because the selective ion channels are highly applicable to diverse fields ranging from fundamental membrane studies to development of ultra-selective biosensors, there have been ceaseless efforts to artificially create the ion channels. In this work, by mimicking the cell membranes in nature, we successfully created ion-selective artificial membranes that contain molecular recognition-based synthetic channels. As the selective permeability system was composed of a freestanding lipid bilayer, ion-binding nucleic acid nanostructure, and hydrophobic anchor for lipid incorporation, it preferentially transported potassium ions among diverse metal ions.